IMC Journal of Medical Science (IMCJMS)

IMC Journal of Medical Science

Formerly Ibrahim Medical College Journal

IMCJMS
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Issue: Vol.13 No.1 - January 2019
Spontaneous hypoglycemia: a review
Authors: Sultana Marufa Shefin,

Affiliations: Department of Endocrinology, BIRDEM General Hospital, 122 Kazi Nazrul Islam Avenue, Shahbag, Dhaka-1000, Bangladesh

Nazmul Kabir Qureshi,

Affiliations: Department of Endocrinology, National Health Care Network, Uttara, Dhaka, Bangladesh

Ahmed Salam Mir,

Affiliations: Department of Endocrinology, Dhaka Central International Medical College, Shyamoly, Dhaka, Bangladesh

Ahasnul Haq Amin,

Affiliations: Apollo Hospital Ltd, Dhaka. Bangladesh

Tareen Ahmed,

Affiliations: Health Education Department, BIRDEM General Hospital, 122 Kazi Nazrul Islam Avenue, Shahbag, Dhaka-1000, Bangladesh

Faria Afsana,

Affiliations: Department of Endocrinolog, BIRDEM General Hospital, 122 Kazi Nazrul Islam Avenue, Shahbag, Dhaka-1000, Bangladesh

Md. Shah Alam,

Affiliations: Comilla Diabetic Hospital, Comilla. Bangladesh

Farhana Akter,

Affiliations: Department of Endocrinology, Chittagong Medical College and Hospital, Chittagong, Bangladesh

Md. Shah Emran,

Affiliations: Department of Endocrinology, MAG Osmani Medical College and Hospital, Sylhet, Bangladesh

Tanjina Hossain,

Affiliations: Department of Endocrinology, Green Life Medical College and Hospital, Green Road, Dhaka, Bangladesh

Md. Shahjamal Khan,

Affiliations: Department of Endocrinology, Enam Medical College and Hospital, Savar, Dhaka, Bangladesh

Marufa Mustari,

Affiliations: Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, Bangladesh

Nusrat Sultana,

Affiliations: Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, Bangladesh

Mohammad Saifuddin,

Affiliations: Abdul Malek Ukil Medical College and Hospital, Noakhali, Bangladesh

Sadiqa Tuqan,

Affiliations: Square Hospital Ltd, Dhaka, Bangladesh

Shahjada Selim,

Affiliations: Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, Bangladesh

Samir Kumar Talukder,

Affiliations: Department of Endocrinology, Rangpur Medical College and Hospital, Rangpur, Bangladesh

Rafiq Uddin,

Affiliations: Department of Endocrinology, Chittagong Medical College and Hospital, Chittagong, Bangladesh

Md. Feroz Amin

Affiliations: Department of Endocrinolog, BIRDEM General Hospital, 122 Kazi Nazrul Islam Avenue, Shahbag, Dhaka-1000, Bangladesh

Spontaneous hypoglycemia is an important entity that may affect multiple organs. The differential diagnosis is broad in individuals with hypoglycemia in the absence of diabetes mellitus. Multiple etiologies may be present concurrently. Drugs, critical illnesses, hormone deficiencies, and non-islet cell tumors should be considered in those who are ill or taking medications. In apparently healthy individuals, endogenous hyperinsulinism due to insulinoma, functional β-cell disorders, or insulin autoimmune conditions are possible, as are accidental, surreptitious or factitious causes of hypoglycemia. Investigations should be guided by clinical scenario. Irrespective of the exact cause of the spontaneous hypoglycemia, treatment consists of correcting the glycemic state and preventing recurrence by alleviating underlying pathology. This review discusses the causes, diagnosis and management of spontaneous hypoglycemia.

IMC J Med Sci 2019; 13(1): 001. EPub date: 24 January 2019. DOI: https://doi.org/10.3329/imcjms.v13i1.42048

Address for Correspondence: Dr. Sultana Marufa Shefin, Assistant Professor, Department of Endocrinology, BIRDEM General Hospital, 122 Kazi Nazrul Islam, Shahbag, Dhaka, Bangladesh. Email: shefin_neon@yahoo.com