THE EFFECT OF GARLIC ON CHOLESTEROL INDUCED HYPERLIPIDAEMIA IN RABITS

Aftab Uddin Ahmed; Syeda Farida Begum; Humaira Naushaba; Md. Noor Islam; Begum Samsun Nahar

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Issue: Vol.1 No.1 - January 2007

THE EFFECT OF GARLIC ON CHOLESTEROL INDUCED HYPERLIPIDAEMIA IN RABITS

Authors:

Aftab Uddin Ahmed

Affiliations

Department of Anatomy,Ibrahim Medical College,Shahbag, Dhaka

,

Syeda Farida Begum

Affiliations

Department of Gynae & Obstetrics,Bangladesh Medical College,Dhanmondi R/A, Dhaka

,

Humaira Naushaba

Affiliations

Department of Anatomy,Sir Salimullah Medical College,Mitford, Dhaka

,

Md. Noor Islam

Affiliations

Department of Anatomy,Ibn Sina Medical College,Kallyanpur, Dhaka

,

Begum Samsun Nahar

Affiliations

Department of Anatomy,Sapporo Dental College,Uttara, Dhaka

An experimental biochemical study was made on rabbits to demonstrate the possible role of aqueous extract of garlic as an antilipidaemic agent in the prevention of hyperlipidaemia. Untreated rabbits on atherogenic diet showed worse lipidaemic status than the normal control ones, as evident in higher serum cholesterol, triglycerides (TG), low-density lipoprotein (LDL) and lower high-density lipoprotein (HDL) level. On the otherhand the rabbits on atherogenic diet treated with aqueous extract of garlic showed significantly better lipidaemic status. It is suggested that aqueous extract of garlic is an important determinant of serum lipid level, which is an antilipidaemic agent against the pathogenesis of atherosclerosis.

Ibrahim Med. Coll. J. 2007; 1(1): 16-20

Address for Correspondence: Prof. Aftab Uddin Ahmed, Department of Anatomy, Ibrahim Medical College, 122 Kazi Nazrul Islam Avenue, Shahbag, Dhaka-1000