https://imcjms.com/public Ibrahim Medical College Journal of Medical Science https://imcjms.com/public/registration/journal_full_text/209 Thu, 04 May 2017 13:21:09 +0000 Secondary hypertension is more common in children compared to that in adults, leading to organ damage and increased mortality. Renal artery stenosis could be a sequel to secondary hypertension in children and give rise to serious outcomes. A case of renal artery stenosis in an eight year old boy is presented in this study in whom PTA was performed with successful results. Blood pressure was controlled and all antihypertensive drugs could be withdrawn in a short period of time. Address for Correspondence:Dr. Syed Dawood Md. Taimur, Department of Cardiology, Ibrahim Cardiac Hospital & Research Institute, 122 Kazi Nazrul Islam Avenue, Shahbagh, Dhaka-1000. Email: dr.sdmtaimur@yahoo.com   An 8-year-old boy presented with history of headache and blurring of vision, weakness in left side of the body for one month. Physical examination revealed a conscious (Glasgow coma scale – 9 to 10), oriented, mildly edematous boy with puffy face. His pulse rate was 120 per minute which was regular in rhythm, and normal in volume. There was no radio-radial and radio-femoral delay. Blood pressure was 190/100 mm Hg in both upper limbs and 180/100 mm Hg in both lower limbs. Common carotid pulsations were equal on both sides. Carotid bruit was absent on both sides though audible only over right renal angle. Examination of cardiovascular system revealed that jugular venous pulsation was not raised. There was no visible cardiac impulse present. Apex beat was placed normally in the left fifth inter-costal space just lateral to mid clavicular line. First and second heart sounds were normally audible and there was absence of murmur. Hematological examination showed that hemoglobin level was 11.9gm / dl, erythrocyte sedimentation rate (ESR) was 30 mm in first hour, total count of red blood cell was 4.44 m/µl and total leukocyte count was 13,900/cumm (Neutrophil-82%, Lymphocyte-13%). Peripheral blood film showed that red blood cells were normocytic and normochromic. There was neutrophillia with cytoplasmic vaculation in some neutrophils, platelets were normal. Liver function tests, serum electrolytes, lipid profile and renal function tests were found normal. HBsAg, Anti-HCV, Anti-HIV and TPHA were negative. Cardiovascular system examination was found normal. Electrocardiographic (ECG) tracing was normal. Radiological examination of chest and echocardiography were found normal. Coronary angiogram showed that epicardial coronary arteries were normal and flash aortogram ruled out coarctation of aorta.   Fig-1a. Right renal artery stenosis     Fig-1b. After PTA of right renal artery For neurological deficiency, computed tomography scan of brain was done. A massive right cerebral infarct with focal hemorrhagic transformation in right temporal region was detected together with one small infarct in left parietal region (Figure 2).   As soon as the diagnosis of stenosed right renal artery was confirmed, a percutaneous transluminal angioplasty (PTA) was done with bare metal stent (3.0X13 mm) in the same setting. The patient was discharged with antihypertensive and anti-platelet drugs. He was advised to continue physiotherapy of affected limbs and to maintain weekly follow-up for a month and fortnightly thereafter. During follow-up, his clinical condition improved significantly. Hematological values, serum creatinine, urine analysis were becoming normal, and more importantly, blood pressure was found controlled with gradual reduction of antihypertensive drugs. However, antihypertensive and anti-platelet medication continued as monitored by follow up. Discussion Aims of the treatment modalities like medical treatment, PTA and surgery are done usually to control blood pressure and preservation of renal function. In our case, we performed PTA, which resulted in controlling blood pressure and finally normotensive with gradual withdrawal of number and doses of several antihypertensive drugs.   1.   National High Blood Pressure Education Program. Working Group on Hypertension in Children and Adolescents. Update on the 1987 Task Force Report on High Blood Pressure in Children and Adolescents. A working group report from the National High Blood Pressure Education Program. Pediatric 1996; 98: 649-658. 3.   Dillon MJ. The diagnosis of renovascular hypertension. Pediatric Nefrol 1997; 11: 366-372. 5.   Estepa R, Gallego N, Orte L, Puras E, Aracil E, Ortuño J. Renovascular hypertension in children. Scand J. Urol Nephrol 2001; 35: 388-392. 7.   McTaggart SJ, Gulati S, Walker RG, Powell HR, Jones CL. Evaluation and long-term outcome of pediatric renovascular hypertension. Pediatr Nephol 2000; 14: 1022-1029. 2026 Ibrahim Medical College. All rights reserved.