Department of Physiology, Ibrahim Medical College, Shahbag, Dhaka, Bangladesh
Department of Physiology, Dhaka Medical College, Dhaka, Bangladesh
and objectives: Infertility is a global
health problem including Bangladesh. Altered prolactin, follicle (FSH) and
luteinizing hormones (LH) levels have been implicated as a cause of
infertility. The present study was undertaken to find out the serum prolactin and
gonadotropin levels in women with primary and secondary infertility.
Methods: The study involved a total of 100 women of which 50
had primary (Group A) and another 50 had secondary (Group B) infertility. Fifty
fertile age-matched women were included as control (Group C). All
the study participants were selected from women attending the infertility unit
of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. Serum prolactin, FSH and LH hormones were
measured by radioimmunoassay with blood collected on the 2nd day of
Results: The mean serum
prolactin level was significantly higher (<p0.01)
while the mean serum FSH and LH levels were significantly(p< 0.01) lower in women
with primary and secondary infertility compared to fertile women. However, the
mean serum prolactin, FSH and LH levels were not significantly different from
each other among the women with primary and secondary sterility. High
prolactinemia was observed in 16% and 14% women in Group A and B respectively.
women with secondary sterility, significantly (p<0.05%) higher number of
cases with primary sterility (30% vs. 54%) had FSH level below the normal
range. On the other hand, 28% cases with secondary sterility had LH level below
the normal range compared to 10% in primary sterility group (p<0.05).
Conclusion: The study has
demonstrated that there was alteration of serum prolactin, FSH and LH levels in
women with primary and secondary sterility.
IMC J Med Sci 2018; 12(1): 01-05
Address for Correspondence:Dr. Shamima Bari, Assistant Professor,
Department of Physiology, Ibrahim Medical College, 122 Kazi Nazrul Islam
Avenue, Shahbag, Dhaka. E-mail: firstname.lastname@example.org